Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.8
USERS' SCORE
Good
Based on 4 Reviews
8.4
Supplement Facts
Serving Size: 2 VegCaps
Amount Per Serving
%DV
Vitamin C (as Ascorbic Acid)
1,235 mg
1,372%
Quercetin
465 mg
*
Bromelain (Supplying 90 MCU)
50 mg
*
Top Medical Research Studies
9
We recently tested a quercetin-based supplement, Cysta-Q, on 22 patients with interstitial cystitis (IC) in an open-label trial. Over 4 weeks, participants took two capsules daily, and we assessed their symptoms before and after treatment.
The results were encouraging; all patients reported improvements in their problem and symptom indices, as well as pain levels. Interestingly, everyone but one individual experienced some positive change, and there were no side effects reported.
These promising findings suggest that quercetin could be beneficial for those suffering from IC, although larger, controlled studies are needed for confirmation.
The results were encouraging; all patients reported improvements in their problem and symptom indices, as well as pain levels. Interestingly, everyone but one individual experienced some positive change, and there were no side effects reported.
These promising findings suggest that quercetin could be beneficial for those suffering from IC, although larger, controlled studies are needed for confirmation.
Read More
8
We sought to understand how quercetin could alleviate chronic pelvic pain associated with Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) using a rat model. Over four weeks, rats received oral quercetin while measuring various blood and prostate health markers.
Our findings revealed that quercetin improved prostate health by reducing inflammation and enhancing antioxidant capacity. Specifically, it lowered levels of harmful inflammatory markers and suppressed certain signaling pathways known to contribute to pain. Overall, quercetin showed significant protective effects against CP/CPPS.
Our findings revealed that quercetin improved prostate health by reducing inflammation and enhancing antioxidant capacity. Specifically, it lowered levels of harmful inflammatory markers and suppressed certain signaling pathways known to contribute to pain. Overall, quercetin showed significant protective effects against CP/CPPS.
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7
We investigated how quercetin, a potential treatment for endometriosis-related pelvic pain, affects endometrial stromal cells. By using cells derived from menstrual effluent of both unaffected individuals and those with endometriosis, we observed quercetin's role in promoting decidualization, which is vital for embryo implantation.
Although the study shows promising mechanisms behind quercetin's effects, the direct benefits on reducing pelvic pain require further clinical exploration. Our findings suggest that while quercetin improves cellular responses, additional studies are needed to confirm its effectiveness as a treatment for chronic pelvic pain.
Although the study shows promising mechanisms behind quercetin's effects, the direct benefits on reducing pelvic pain require further clinical exploration. Our findings suggest that while quercetin improves cellular responses, additional studies are needed to confirm its effectiveness as a treatment for chronic pelvic pain.
Read More
Most Useful Reviews
9
Pelvic pain relief
2 people found this helpful
Sinus forehead pain has disappeared within a week. Last October, I experienced consistent forehead sinus pain, particularly when lowering my head. I began taking this supplement twice daily, with one capsule each time. After just one week, my pain has vanished.
Read More
9
Pain alleviation achieved
1 people found this helpful
Under Polinoza is superb, especially for spring pollen allergies. My eyes experienced aching, dryness, and discomfort. After taking two capsules, I could immediately sense the relief from these unpleasant sensations. Fantastic!
Read More
7.5
Pain reduction noted
1 people found this helpful
This quercetin is effective; I consume two capsules on an empty stomach both morning and evening. Dr. Petrik introduced me to this supplement. I've noticed a difference as local inflammations have disappeared, and while the varicose veins remain, the discomfort in my legs has completely subsided. Overall, I feel much better.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.8
- All Researches
9
Quercetin shows promise for endometriosis pain
We explored the effectiveness of a combination treatment involving quercetin, curcumin, and acetylcysteine for easing pelvic pain in women with endometriosis. In this study, 33 women took the supplement daily for two months while we monitored their pain levels related to dysmenorrhea, pelvic pain, and dyspareunia.
The results were promising, showing a significant reduction in pain symptoms and decreased reliance on NSAIDs. We observed that this treatment may serve as a helpful addition to managing endometriosis-related pain without notable side effects.
The results were promising, showing a significant reduction in pain symptoms and decreased reliance on NSAIDs. We observed that this treatment may serve as a helpful addition to managing endometriosis-related pain without notable side effects.
Read More
9
Quercetin alleviates pelvic pain
We explored the effects of Phyllanthus niruri extract and its isolated components, including quercetin, on hemorrhagic cystitis induced by cyclophosphamide in mice. The study involved treatment before and after inducing the condition and assessed pain, swelling, and bleeding.
We found that quercetin led to significant pain relief, while other compounds like gallic acid and rutin showed notable anti-inflammatory effects. Overall, the extract and its components proved beneficial in alleviating the treatment's side effects, suggesting potential therapeutic value.
We found that quercetin led to significant pain relief, while other compounds like gallic acid and rutin showed notable anti-inflammatory effects. Overall, the extract and its components proved beneficial in alleviating the treatment's side effects, suggesting potential therapeutic value.
Read More
9
We examined the effects of multimodal therapy on chronic pelvic pain using the UPOINT system. After 27 weeks, 100 patients receiving tailored treatments, including quercetin for organ-specific symptoms, showed notable improvement.
About 84% experienced significant symptom reduction, highlighting a median drop in pain scores from 11.5 to 6.1. While quercetin appeared beneficial, there was no guarantee that the number of symptoms predicted the outcome. Overall, this approach signifies a step forward in managing chronic pelvic pain effectively.
About 84% experienced significant symptom reduction, highlighting a median drop in pain scores from 11.5 to 6.1. While quercetin appeared beneficial, there was no guarantee that the number of symptoms predicted the outcome. Overall, this approach signifies a step forward in managing chronic pelvic pain effectively.
Read More
9
We recently tested a quercetin-based supplement, Cysta-Q, on 22 patients with interstitial cystitis (IC) in an open-label trial. Over 4 weeks, participants took two capsules daily, and we assessed their symptoms before and after treatment.
The results were encouraging; all patients reported improvements in their problem and symptom indices, as well as pain levels. Interestingly, everyone but one individual experienced some positive change, and there were no side effects reported.
These promising findings suggest that quercetin could be beneficial for those suffering from IC, although larger, controlled studies are needed for confirmation.
The results were encouraging; all patients reported improvements in their problem and symptom indices, as well as pain levels. Interestingly, everyone but one individual experienced some positive change, and there were no side effects reported.
These promising findings suggest that quercetin could be beneficial for those suffering from IC, although larger, controlled studies are needed for confirmation.
Read More
9
We examined the potential of quercetin, a bioflavonoid, in alleviating pelvic pain in men with chronic prostatitis syndromes. In a randomized, double-blind trial involving 30 men, those taking quercetin experienced a notable reduction in symptoms compared to those on a placebo.
Specifically, 67% of men on quercetin showed a 25% improvement in symptoms, compared to just 20% in the placebo group. Even more encouraging, a follow-up with additional participants using a quercetin combination showed an impressive 82% improvement. Overall, quercetin is well tolerated and may significantly help for many facing chronic pelvic pain.
Specifically, 67% of men on quercetin showed a 25% improvement in symptoms, compared to just 20% in the placebo group. Even more encouraging, a follow-up with additional participants using a quercetin combination showed an impressive 82% improvement. Overall, quercetin is well tolerated and may significantly help for many facing chronic pelvic pain.
Read More
User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
9
Pelvic pain relief
2 people found this helpful
Sinus forehead pain has disappeared within a week. Last October, I experienced consistent forehead sinus pain, particularly when lowering my head. I began taking this supplement twice daily, with one capsule each time. After just one week, my pain has vanished.
Read More
9
Pain alleviation achieved
1 people found this helpful
Under Polinoza is superb, especially for spring pollen allergies. My eyes experienced aching, dryness, and discomfort. After taking two capsules, I could immediately sense the relief from these unpleasant sensations. Fantastic!
Read More
7.5
Pain reduction noted
1 people found this helpful
This quercetin is effective; I consume two capsules on an empty stomach both morning and evening. Dr. Petrik introduced me to this supplement. I've noticed a difference as local inflammations have disappeared, and while the varicose veins remain, the discomfort in my legs has completely subsided. Overall, I feel much better.
Read More
7.5
Effective anti-inflammatory
This vitamin C is excellent, offering the benefits of ascorbic acid and bromelain. I appreciate bromelain's strong anti-inflammatory properties, which significantly alleviate pain. I highly recommend it!
Read More
Frequently Asked Questions
9
Pelvic pain relief
2 people found this helpful
Sinus forehead pain has disappeared within a week. Last October, I experienced consistent forehead sinus pain, particularly when lowering my head. I began taking this supplement twice daily, with one capsule each time. After just one week, my pain has vanished.
9
Pain alleviation achieved
1 people found this helpful
Under Polinoza is superb, especially for spring pollen allergies. My eyes experienced aching, dryness, and discomfort. After taking two capsules, I could immediately sense the relief from these unpleasant sensations. Fantastic!
7.5
Pain reduction noted
1 people found this helpful
This quercetin is effective; I consume two capsules on an empty stomach both morning and evening. Dr. Petrik introduced me to this supplement. I've noticed a difference as local inflammations have disappeared, and while the varicose veins remain, the discomfort in my legs has completely subsided. Overall, I feel much better.
9
Quercetin shows promise for endometriosis pain
We explored the effectiveness of a combination treatment involving quercetin, curcumin, and acetylcysteine for easing pelvic pain in women with endometriosis. In this study, 33 women took the supplement daily for two months while we monitored their pain levels related to dysmenorrhea, pelvic pain, and dyspareunia.
The results were promising, showing a significant reduction in pain symptoms and decreased reliance on NSAIDs. We observed that this treatment may serve as a helpful addition to managing endometriosis-related pain without notable side effects.
The results were promising, showing a significant reduction in pain symptoms and decreased reliance on NSAIDs. We observed that this treatment may serve as a helpful addition to managing endometriosis-related pain without notable side effects.
7
UPOINT therapy shows symptom improvement
We explored the effectiveness of UPOINT-guided multimodal therapy in managing chronic prostatitis and chronic pelvic pain syndrome. Our study involved 110 men aged 26 to 68, where we compared an intervention group receiving a tailored treatment, including 1g of Quercetin, to a control group with no therapy.
After treatment, we observed notable improvements in symptom scores and overall quality of life for the intervention group. This suggests that multimodal therapy, which includes Quercetin, could be beneficial for men suffering from this painful condition.
After treatment, we observed notable improvements in symptom scores and overall quality of life for the intervention group. This suggests that multimodal therapy, which includes Quercetin, could be beneficial for men suffering from this painful condition.
4
We investigated whether genetic variations could influence treatment success for chronic pelvic pain syndrome. Our research involved analyzing the DNA of 36 men with this condition and comparing their genetic markers to 252 control participants.
We found that those with a specific low IL-10 producing genotype were more common among patients experiencing chronic pelvic pain. Specifically, quercetin, an anti-inflammatory treatment, was less effective in patients with low TNF-alpha genotypes. This suggests the importance of genetic factors in determining how well quercetin works for relieving pelvic pain.
We found that those with a specific low IL-10 producing genotype were more common among patients experiencing chronic pelvic pain. Specifically, quercetin, an anti-inflammatory treatment, was less effective in patients with low TNF-alpha genotypes. This suggests the importance of genetic factors in determining how well quercetin works for relieving pelvic pain.
8
Deprox® outperforms quercetin in symptoms
We explored the effects of flower pollen extracts (Deprox®) versus quercetin on chronic pelvic pain in men diagnosed with chronic prostatitis/chronic pelvic pain syndrome. In our study with 54 patients, we found that Deprox® significantly improved symptoms and quality of life, along with a faster response time in alleviating pain, compared to quercetin. Notably, quercetin did not show significant benefits in this context. This suggests that while quercetin may be beneficial, it wasn’t as effective as the flower pollen extract in enhancing patient well-being.
References
- Delenko J, Xue X, Chatterjee PK, Hyman N, Shih AJ, et al. Quercetin enhances decidualization through AKT-ERK-p53 signaling and supports a role for senescence in endometriosis. Reprod Biol Endocrinol. 2024;22:100. doi:10.1186/s12958-024-01265-z
- Liu H, Wang Z, Xie Q, Chi A, Li Y, et al. Ningmitai capsules have anti-inflammatory and pain-relieving effects in the chronic prostatitis/chronic pelvic pain syndrome mouse model through systemic immunity. Front Pharmacol. 2022;13:949316. doi:10.3389/fphar.2022.949316
- Fadin M, Nicoletti MC, Pellizzato M, Accardi M, Baietti MG, et al. Effectiveness of the integration of quercetin, turmeric, and N-acetylcysteine in reducing inflammation and pain associated with endometriosis. In-vitro and in-vivo studies. Minerva Ginecol. 2020;72:285. doi:10.23736/S0026-4784.20.04615-8
- Krakhotkin DV, Chernylovskyi VA, Bakurov EE, Sperl J. Evaluation of influence of the UPOINT-guided multimodal therapy in men with chronic prostatitis/chronic pelvic pain syndrome on dynamic values NIH-CPSI: a prospective, controlled, comparative study. Ther Adv Urol. 2019;11:1756287219857271. doi:10.1177/1756287219857271
- Maurizi A, De Luca F, Zanghi A, Manzi E, Leonardo C, et al. The role of nutraceutical medications in men with non bacterial chronic prostatitis and chronic pelvic pain syndrome: A prospective non blinded study utilizing flower pollen extracts versus bioflavonoids. Arch Ital Urol Androl. 2019;90:260. doi:10.4081/aiua.2018.4.260
- Park S, Lim W, Bazer FW, Whang KY, Song G. Quercetin inhibits proliferation of endometriosis regulating cyclin D1 and its target microRNAs in vitro and in vivo. J Nutr Biochem. 2019;63:87. doi:10.1016/j.jnutbio.2018.09.024
- Meng LQ, Yang FY, Wang MS, Shi BK, Chen DX, et al. Quercetin protects against chronic prostatitis in rat model through NF-κB and MAPK signaling pathways. Prostate. 2018;78:790. doi:10.1002/pros.23536
- Schiavi MC, Porpora MG, Vena F, Prata G, Sciuga V, et al. Orally Administered Combination of Hyaluronic Acid, Chondroitin Sulfate, Curcumin, and Quercetin in the Prevention of Postcoital Recurrent Urinary Tract Infections: Analysis of 98 Women in Reproductive Age After 6 Months of Treatment. Female Pelvic Med Reconstr Surg. 2019;25:309. doi:10.1097/SPV.0000000000000560
- Güney G, Kaya C, Oto G, Yıldırım S, Özdemir H, et al. Effects of quercetin and surgicel for preventing adhesions after gynecological surgery: A rat uterine horn model. J Obstet Gynaecol Res. 2017;43:179. doi:10.1111/jog.13185
- Boeira VT, Leite CE, Santos AA, Edelweiss MI, Calixto JB, et al. Effects of the hydroalcoholic extract of Phyllanthus niruri and its isolated compounds on cyclophosphamide-induced hemorrhagic cystitis in mouse. Naunyn Schmiedebergs Arch Pharmacol. 2011;384:265. doi:10.1007/s00210-011-0668-0
- Shoskes DA, Nickel JC, Kattan MW. Phenotypically directed multimodal therapy for chronic prostatitis/chronic pelvic pain syndrome: a prospective study using UPOINT. Urology. 2010;75:1249. doi:10.1016/j.urology.2010.01.021
- Shoskes DA, Hakim L, Ghoniem G, Jackson CL. Long-term results of multimodal therapy for chronic prostatitis/chronic pelvic pain syndrome. J Urol. 2003;169:1406.
- Shoskes DA, Albakri Q, Thomas K, Cook D. Cytokine polymorphisms in men with chronic prostatitis/chronic pelvic pain syndrome: association with diagnosis and treatment response. J Urol. 2002;168:331.
- Katske F, Shoskes DA, Sender M, Poliakin R, Gagliano K, et al. Treatment of interstitial cystitis with a quercetin supplement. Tech Urol. 2001;7:44.
- Shoskes DA, Zeitlin SI, Shahed A, Rajfer J. Quercetin in men with category III chronic prostatitis: a preliminary prospective, double-blind, placebo-controlled trial. Urology. 1999;54:960.
